Nicholas Gigliotti obtained a BS in Materials Science and Engineering from The Pennsylvania State University and a PhD in Materials Science and Engineering from Johns Hopkins University. During his graduate training, his research focused on the mechanobiology of fibrous extracellular matrix (ECM), investigating how enzymatic crosslinking and remodeling dynamically shape the structural and mechanical properties of collagen networks in the cervix during pregnancy using a combination of multi-modal microscopy, mechanical characterization, and molecular simulation.

In January 2026, Gigliotti joined the Johns Hopkins University Whiting School of Engineering as an assistant research scientist. His current research interests lie in ECM biology and biomaterial design, with a focus on translating fundamental insights into the mechanics and remodeling of collagen-based matrices toward solutions in women’s health, wound healing, fibrosis, anti-aging, and metabolic disease.