MM roundtable Slide Slide

The Role of Physical Cues in Collective Cell In Invasion

A hallmark of cancer is the spread, or metastasis, of cells from the tumor to distant tissues and organs. This project looks at how the physical forces exerted upon cancer cells by confinement within a tumor can regulate the migration of these cells, both collectively and alone.

Forces Involved in Collective Cell Migration

Pathologic and in vivo experimental evidence tells us that cancer cells like to travel in groups as they leave a tumor site and spread to other parts of the body. In this project, we investigate the forces involved in organizing the collective migration of breast cancer cells in both 2D and 3D environments.

Impact of Low Oxygen on the Migration of Sarcoma Cells

Low oxygen in a tumor (hypoxia) dramatically increases pulmonary metastasis and results in poor clinical outcomes. However, little is known about the effects of hypoxia on sarcoma cells and the microenvironment. In this project, we are learning how primary tumor cells respond to oxygen in their microenvironment.

News

Events

Oct
16
Fri
Vernon Rice Memorial Turkey Program
Oct 16 – Dec 11 all-day
Vernon Rice Memorial Turkey Program

The INBT and PS-OC is encouraging the community to participate in the Vernon Rice Memorial Turkey Program, which supports Baltimore families. For every $25 raised, a basket with a fresh turkey and vegetables from a local farm will be provided to a family in need. Learn more about Vernon Rice, the program, and how to donate.

Donations for the Thanksgiving holiday are due November 13, 2020. Donations for the December holidays are due December 11, 2020.