Welcome to to the website of Dr. Thomas Pisanic and the Epidiagnostics Group at Johns Hopkins University! I work with the Wang laboratory and an interdisciplinary team of JHU researchers to gain deeper insight into the epigenetics of carcinogenesis and apply this knowledge toward the development of novel microfluidic molecular analysis platforms for cancer diagnostic applications. Our “epidiagnostics” team is comprised of faculty with a wide range of complementary expertise, including: Dr. Thomas Pisanic (epigenetics, biomarker discovery and assay development), Dr. Tza-Huei Wang (bioengineering and microfluidic technologies), Dr. Hari Easwaran (genetics and epigenetics of cancer and aging) and Dr. Leslie Cope (biostatistics and bioinformatics). Together, we work with numerous collaborators from Johns Hopkins and beyond to apply our epigenetic methods to resolve manifold challenges in various areas of cancer research.
|May 16, 2023
|Working to Detect Ovarian Cancer Earlier (INBT Press Release)
|Apr 25, 2023
|Break Through Cancer, A New Research Consortium, Names First Class of Scientists Designated as Catalysts for Innovation and Collaboration (BTC Press Release)
|Jul 1, 2022
|Dr. Pisanic appointed as Associate Research Professor at INBT with joint appointment in the SOM Department of Oncology.
|Apr 22, 2022
|Break Through Cancer Announces $50M in Grants to Support Team Science!
|Mar 1, 2022
|Dr. Pisanic appointed as Break Through Cancer Scientist!
CancersCurrent and Emerging Methods for Ovarian Cancer Screening and Diagnostics: A Comprehensive ReviewCancers, 2022
Clin. EpigeneticsLeveraging locus-specific epigenetic heterogeneity to improve the performance of blood-based DNA methylation biomarkersClinical Epigenetics, 2020
Clin. Cancer Res.Methylomic Landscapes of Ovarian Cancer Precursor LesionsClinical Cancer Research, 2020
Sci. Adv.Facile profiling of molecular heterogeneity by microfluidic digital meltScience Advances, 2018
Nucleic Acids Res.DREAMing: a simple and ultrasensitive method for assessing intratumor epigenetic heterogeneity directly from liquid biopsiesNucleic Acids Research, 2015