{"id":2361,"date":"2013-05-15T06:13:37","date_gmt":"2013-05-15T06:13:37","guid":{"rendered":"https:\/\/inbt.jhu.edu\/psoc\/?p=2361"},"modified":"2019-05-02T06:14:57","modified_gmt":"2019-05-02T06:14:57","slug":"recent-publications-from-the-johns-hopkins-physical-sciences-oncology-center","status":"publish","type":"post","link":"https:\/\/inbt.jhu.edu\/psoc\/recent-publications-from-the-johns-hopkins-physical-sciences-oncology-center\/","title":{"rendered":"Recent publications from the Johns Hopkins Physical Sciences-Oncology Center"},"content":{"rendered":"<div id=\"ip-content\">\n<div id=\"ip-content\">\n<p>Johns Hopkins Physical Sciences-Oncology Center has had a productive quarter publishing from February to May 2013. Here are some of the most recent publications in support or the center\u2019s core research projects, including a huge collaborative work drawing on the knowledge and research findings of the entire PS-OC network.<\/p>\n<\/div>\n<p>That paper, <b>A physical sciences network characterization of non-tumorigenic and metastatic cells<\/b>, was the work of 95 authors from all 12 of the National Cancer Institute\u2019s PS-OC \u00a0program centers. JHU\u2019s PS-OC director Denis Wirtz, the Theophilus H. Smoot Professor in the Johns Hopkins Department of Chemical and Ciomolecular Engineering, is the corresponding author on this massive effort. We will be discussing the findings of that paper in a future post here on the PS-OC website. Until then, here is a link to that network paper and 13 other recent publications from the Johns Hopkins PS-OC.<\/p>\n<ul>\n<li><b>A physical sciences network characterization of non-tumorigenic and metastatic cells.<\/b>Physical Sciences \u2013 Oncology Centers Network, Agus DB, Alexander JF, Arap W,Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC,Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P,Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J,Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S,Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, HielscherA, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE,Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P,Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, LloydMC, Lyubimova A, Mallick P, Marko J, McCarty OJ, Meldrum DR, Michor F,Mumenthaler SM, Nandakumar V, O\u2019Halloran TV, Oh S, Pasqualini R, Paszek MJ,Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P,Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, TormoenGW, Tseng Y, van Oudenaarden A, Verbridge SS, Wan JC, Weaver VM, Widom J, Will C, Wirtz D, Wojtkowiak J, Wu PH.\u00a0 Sci Rep. 2013 Apr 25;3:1449. doi:10.1038\/srep01449. PubMed PMID: 23618955; PubMed Central PMCID: PMC3636513.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23618955\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23618955<\/a><\/li>\n<li><b>Procollagen Lysyl Hydroxylase 2 Is Essential for Hypoxia-Induced Breast Cancer Metastasis. <\/b>Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL.Mol Cancer Res. 2013 May 7. [Epub ahead of print] PubMed PMID:\u00a023378577.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23378577\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23378577<\/a><\/li>\n<li><b>Predicting how cells spread and migrate: Focal adhesion size does matter.\u00a0<\/b>Kim DH, Wirtz D.\u00a0Cell Adh Migr. 2013 Apr 29;7(3). [Epub ahead of print] PubMed PMID: 23628962.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23628962\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23628962<\/a><\/li>\n<li><b>Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by Inducing P4HA1, P4HA2, and PLOD2 Expression in Fibroblasts<\/b>.\u00a0Gilkes DM, Bajpai S, Chaturvedi P, Wirtz D, Semenza GL.\u00a0J Biol \u00a0\u00a0Chem. 2013 Apr 12;288(15):10819-29. doi: 10.1074\/jbc.M112.442939. Epub 2013 Feb 19. PubMed PMID: 23423382; PubMed Central PMCID: PMC3624462.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23423382\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23423382<\/a><\/li>\n<li><b>Perivascular cells in blood vessel regeneration.\u00a0<\/b>Wanjare M, Kusuma S, Gerecht S.\u00a0Biotechnol J. 2013 Apr;8(4):434-47. doi: 10.1002\/biot.201200199.\u00a0PubMed PMID: 23554249.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23554249\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23554249<\/a><\/li>\n<li><b>Focal adhesion size uniquely predicts cell migration.\u00a0<\/b>Kim DH, Wirtz D.\u00a0FASEB\u00a0J. 2013 Apr;27(4):1351-61. doi: 10.1096\/fj.12-220160. Epub 2012 Dec 19. PubMed\u00a0PMID: 23254340; PubMed Central PMCID: PMC3606534.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23254340\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23254340<\/a><\/li>\n<li><b>Notch4-dependent Antagonism of Canonical TGF\u03b21\u00a0 Signaling Defines Unique Temporal Fluctuations of SMAD3 Activity in Sheared Proximal Tubular Epithelial Cells.<\/b> Grabias BM, Konstantopoulos K. Am J Physiol Renal Physiol. 2013 Apr 10. [Epub ahead of print] PubMed PMID: 23576639.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23576639\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23576639<\/a><\/li>\n<li><b>Integration and regression of implanted engineered human vascular networks during deep wound healing.\u00a0<\/b>Hanjaya-Putra D, Shen YI, Wilson A, Fox-Talbot K, Khetan S, Burdick JA,\u00a0Steenbergen C, Gerecht S.\u00a0Stem Cells Transl Med. 2013\u00a0Apr;2(4):297-306. doi: 10.5966\/sctm.2012-0111. Epub 2013 Mar 13. PubMed PMID: 23486832.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23486832\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23486832<\/a><\/li>\n<li><b>Collagen Prolyl Hydroxylases are Essential for Breast Cancer\u00a0<\/b><b>Metastasis.\u00a0<\/b>Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, Hubbi ME, Wirtz\u00a0D, Semenza GL.\u00a0Cancer Res. 2013 Mar 28. [Epub ahead of print] PubMed PMID: 23539444.\u00a0h<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23539444\">ttp:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23539444<\/a><\/li>\n<li><b>Simultaneously defining cell phenotypes, cell cycle, and chromatin modifications at single-cell resolution.<\/b>Chambliss AB, Wu PH, Chen WC, Sun SX, Wirtz D.FASEB J. 2013 Mar 28. [Epub ahead of print] PubMed PMID: 23538711.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23538711\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23538711<\/a><\/li>\n<li><b>Interstitial friction greatly impacts membrane mechanics.<\/b> Wirtz D. Biophys J.2013 Mar 19;104(6):1217-8. doi: 10.1016\/j.bpj.2013.02.003. Epub 2013 Mar 19.PubMed PMID: 23528079; PubMed Central PMCID: PMC3602747.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23528079\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23528079<\/a><\/li>\n<li><b>Functional interplay between the cell cycle and cell phenotypes.\u00a0<\/b>Chen WC, Wu PH, Phillip JM, Khatau SB, Choi JM, Dallas MR, Konstantopoulos K,Sun SX, Lee JS, Hodzic D, Wirtz D.Integr Biol (Camb). 2013 Mar;5(3):523-34. doi:10.1039\/c2ib20246h. PubMed PMID: 23319145\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23319145\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23319145<\/a><\/li>\n<li><b>High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity<\/b>. Lu Y, Chen JJ, Mu L, Xue Q, Wu Y, Wu PH, Li J, Vortmeyer AO, Miller-Jensen K, Wirtz D, Fan R. Anal Chem. 2013 Feb 19;85(4):2548-56. doi:10.1021\/ac400082e. Epub 2013 Feb 1. PubMed PMID: 23339603; PubMed Central PMCID: \u00a0PMC3589817.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23339603\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23339603<\/a><\/li>\n<\/ul>\n<\/div>\n<div>Story by: INBT<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Johns Hopkins Physical Sciences-Oncology Center has had a productive quarter publishing from February to May 2013. Here are some of the most recent publications in support or the center\u2019s core research projects, including a huge collaborative work drawing on the knowledge and research findings of the entire PS-OC network.&hellip;<\/p>\n","protected":false},"author":16,"featured_media":2362,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2361","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/posts\/2361","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/comments?post=2361"}],"version-history":[{"count":1,"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/posts\/2361\/revisions"}],"predecessor-version":[{"id":2363,"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/posts\/2361\/revisions\/2363"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/media\/2362"}],"wp:attachment":[{"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/media?parent=2361"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/categories?post=2361"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inbt.jhu.edu\/psoc\/wp-json\/wp\/v2\/tags?post=2361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}