All are welcome to attend our hybrid 15th Nano-Bio Symposium on Engineering Genes and Genomes.

From draft sequencing the human genome in 2001, to the development of CRISPR editing tools in 2012, to the first FDA approved gene therapy in 2017, recent progress in genetics and genomics has been astonishing. This year’s symposium will feature the frontiers of this exciting bioengineering research with lectures, panels, and posters to showcase diverse approaches to interrogate genome structure and manipulate gene products. Attendees will learn about nanoscale system developments to deliver gene therapies in tissue and cell specific ways, RNA regulatory dynamics that govern how genotype manifests as phenotype, genomic tagging to reveal lineage relationships in development and disease, and how to bring these advances to patients through safe, efficacious, and equitable genetic medicine development. By surveying this progress, engineers, biologists, and their partners can better understand the grand challenges to altering biological systems.

This is a hybrid event where the lectures and panels will be virtual and the poster session with a reception will be in-person.

Attendance and Registration

Lectures
The lectures will be held on the Zoom platform.  A Zoom link will be emailed to registrants as the event approaches. Registration for the lectures closes June 9, 2022 at 5:00 pm ET. 

Poster Competition and Reception
The poster session and reception will be in the Mudd Hall atrium located on the ground level on the Johns Hopkins Homewood campus. Students who wish to present a poster can register using the general registration link. Poster registration closes Sunday, June 5, 2022 at 5:00 pm ET and is capped to the first 60 posters registered. Read poster information guidelines before you register your poster.

Poster prizes
Undergraduate prizes: Two at $500 each.
Masters/PhD/Postdoc prizes: 1st prize $800, 2nd prize $600 prize, and 3rd prize $400.

Accessibility

Auto-generated closed captioning will be available on the Zoom platform. The Mudd Hall atrium is located on the ground level and has automatic doors. If other accessibility needs are needed please contact Gina Wadas at ginawadas@jhu.edu

Directions, Maps, and Transportation

The closest parking garage to Mudd Hall is the San Martin parking garage. You can find maps, directions, parking, and shuttle information to the Johns Hopkins Homewood campus here.

Agenda

T.E. Schlesinger, PhD
Benjamin T. Rome Dean, Whiting School of Engineering
Professor of Electrical and Computer Engineering, Johns Hopkins University

Hai-Quan Mao, PhD
Director, Institute for NanoBioTechnology
Professor of Materials Science and Engineering, and Biomedical Engineering
Johns Hopkins University

George Church, PhD
Professor of Genetics, Harvard Medical School
Professor of Health Sciences and Technology, Harvard Medical School and MIT

Introduction by Reza Kalhor
Assistant Professor of Biomedical Engineering, Johns Hopkins School of Medicine

Efie Kokkoli, PhD
Engineering Targeted Nanoparticles for RNA Delivery
Professor of Chemical and Biomolecular Engineering
Johns Hopkins University

Reza Kalhor, PhD
Understanding Cell Fate Through Genomic Barcodes
Assistant Professor of Biomedical Engineering, Johns Hopkins School of Medicine

Jeff Coller, PhD
Harnessing RNA Metabolism for Precision RNA Therapeutics
Bloomberg Distinguished Professor of RNA Biology and Therapeutics, Johns Hopkins University School of Medicine
Department of Molecular Biology and Genetics
Johns Hopkins School of Medicine

Jordan Green, PhD
Polymeric Nanoparticles for Cell-Specific Gene Delivery Without Targeting Ligands
Professor of Biomedical Engineering, Johns Hopkins University

Taekjip (TJ) Ha, PhD
Very Fast CRISPR on Demand
Bloomberg Distinguished Professor
Departments of Biophysics and Biomedical Engineering, Johns Hopkins University

Moderator: Hai-Quan Mao

Steven Altschuler, MD
Managing Director of Healthcare Ventures at Ziff Capital
Co-founder Spark Therapeutics
Former CEO of Children’s Hospital of Pennsylvania

Steven Altschuler brings nearly 20 years of experience building and leading world-class, integrated, translational, value-based health care systems and transformational biotechnology companies. He currently serves as managing director of Healthcare Ventures at Ziff Capital Partners and was previously chair of the board of directors at Spark Therapeutics (now part of Roche) for six years, from its founding until it was acquired in 2019. In his role at Ziff Capital Partners, Dr. Altschuler co-leads the firm’s efforts towards investing in, and facilitating the startup and development of, companies with potentially transformative technologies that emphasize cellular and molecular approaches to human disease.

He previously co-founded Spark Therapeutics to develop and commercialize the preclinical and clinical gene therapy programs advanced at the Children’s Hospital of Philadelphia (CHOP) and other institutions. He served as Spark’s board chair from its founding through its acquisition in 2019, which included leading the company through a successful transition to a public company and the launch of an approved commercial product, which was the first gene therapy for an inherited disease approved by the U.S. Food and Drug Administration and European Medicines Agency. Dr. Altschuler formerly held chief executive positions at CHOP and University of Miami Health System. He is a member of the board of directors of WW (formerly Weight Watchers International), Orchard Therapeutics,  AsclepiX Therapeutics, ImVaX and Platelet Biogenesis. He is also an independent trustee of the Brigham and Women’s Physician Organization at Mass General Brigham. Dr. Altschuler holds a B.A. in mathematics and an M.D. from Case Western Reserve University.

Introduction by Sashank Reddy, MD, PhD
Associate Director, INBT
Departments of Plastic and Reconstructive Surgery, and Biomedical Engineering,
Johns Hopkins University School of Medicine

Daniel Siegwart, PhD
Associate Professor, Department of Biochemistry and the Simmons Comprehensive Cancer Center
The University of Texas Southwestern Medical Center

Anthony Philippakis, MD, PhD
Chief Data Officer and Co-Director of the Eric and Wendy Schmidt Center, Broad Institute
Venture Partner, Google Ventures

Jeff Coller, PhD
Bloomberg Distinguished Professor of RNA Biology and Therapeutics, Johns Hopkins University School of Medicine
Department of Molecular Biology and Genetics
Johns Hopkins School of Medicine

Steven Altschuler, MD
Managing Director of Healthcare Ventures at Ziff Capital

Moderators: Sashank Reddy and Christy Wyskiel, Senior Advisor to the President of Johns Hopkins University and Executive Director of Johns Hopkins Technology Ventures

Refreshments will be served.

Poster Session A: 1:30 pm – 2:30 pm
Poster Session B: 2:40 pm – 3:40 pm

Hai-Quan Mao, PhD
Director, Institute for NanoBioTechnology
Professor of Materials Science and Engineering, and Biomedical Engineering
Johns Hopkins University