Hope for severe burns could lie in the healing action encouraged by a colorless, odorless “hydrogel” developed by Johns Hopkins Institute for NanoBiotechnology affiliated researchers. The Johns Hopkins Engineering Magazine summer edition featured a story here on this work, occurring in the laboratory of chemical and biomolecular engineering associate professor, Sharon Gerecht.
News of the original research was posted here on the INBT blog in December 2011. However, the pain and suffering experienced by third-degree burn sufferers is long-lasting and this work rightly deserves to be re-visited. The original study, done in conjunction with faculty in the Department of Pathology at the Johns Hopkins School of Medicine and the Johns Hopkins Burn Center at Bayview Medical Center, demonstrated for the first time a treatment that could not only aid in healing but practically restore the skin in the tested animals to a healthy state. Use of the hydrogel was tested on mice, and after just a few weeks, skin had regrown to a nearly scar-free state that could even regrow hair. The team is now looking a testing the gel with pigs.
The funny thing is, is that Gerecht and company are not even sure why the hydrogel works the way it does.
The Whiting School of Engineering magazine article highlights the potential commercialization timeline for the hydrogel, that is, when will a product based on this new technology be available for humans? That is a question that folks here at INBT and those affiliated with this work have been receiving nearly once a week since this research was first published. Now, maybe we will have an answer for all those who could potentially benefit from this important and yet mysterious discovery.