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Courses

All predoctoral fellows must complete all course requirements of their home department. Below are the required courses that predoctoral and postdoctoral NTCR fellows must successfully complete.

Nanotechnology for Biology and Medicine

This course covers the physics and chemistry relevant to the design, synthesis, and characterization of nanoparticles and patterned surfaces for biological applications. Topics include nanoparticle synthesis, functionalization, surface engineering, and applications in diagnostics and therapeutics. The properties of semiconductor quantum dots and magnetic nanoparticles are reviewed along with techniques for nanoparticle manipulation, particle tracking, and bio-microrheology. Patterning tools including soft lithography, optical lithography, e-beam lithography, and template lithography is discussed. Electron and scanning probe microscopy are reviewed. Examples applications in cancer is drawn directly from research in participating NTCR research labs.

Molecular Cell Biology of Cancer

 This course introduces fellows with a physics/engineering graduate background to modern concepts in molecular and cellular biology with examples taken from cancer immunology and cancer cell biology.

Fundamentals and topics covered in this course include, but are not limited to:

  • Molecular biology: control of gene expression, microarray technology and modern molecular biology techniques
  • Cancer cell transformation, metastasis, cancer genetics
  • Cell membrane and organelles
  • Evolution of lipid diversity and membrane structure and dynamics
  • Organization, dynamics, and function of the nucleus
  • The cytoskeleton and cancer cell migration
  • ER-Golgi trafficking: traffic through the endosomal process, the fusion machinery, specificity, and regulation of trafficking

Lab course in Cancer Nanobiotechnology

 This lab course is a cornerstone of the training that all NTCR fellows acquire. The main objective is to reveal the basics of biological systems to engineers in the physical sciences and of physical systems to biologists. This lab course takes place in new state-of-the-art facilities that have been equipped with funding from the Howard Hughes Medical Institute and the National Science Foundation.

Lab skills learned include:

  • Physical and chemical tools to characterize and manipulate the properties of surfaces and nanoparticles
  • Synthesis, ligand-functionalization, characterization, and targeted cell intake of multi-functional nanoparticles (nanowires and quantum dots)
  • Atomic force microscopy and quantitative fluorescence microscopy for biological and materials applications.

Accepted fellows with a physics/engineering background will learn the basics of mammalian cell culture, molecular biology, cell transfection/transformation, and blotting techniques.

The following departments have approved these of the courses to count towards the elective requirements for their PhD:

Biology, Biomedical Engineering, Chemical & Biomolecular Engineering, Chemistry, Civil Engineering, Electrical & Computer Engineering, Materials Science & Engineering, Mechanical Engineering, and Physics

 
 
 

 

For questions about INBT's education programs contact: Camille Mathis / cmathis@jhu.edu / 410-516-6572