NanoBio Graduate Programs

Johns Hopkins was recently awarded two graduate training grant programs – from the National Science Foundation and Howard Hughes Medical Institute – that are being facilitated through INBT.

A Howard Hughes Medical Institute (HHMI) educational grant is funding a new graduate training program in nanotechnology for biology and medicine (NBMed) at Johns Hopkins. The program aims to train engineers and scientists to become adept in the creation of new particles and materials for use in the detection, treatment, prevention, and cure of human disease. Hopkins departments included: Biology, Biomedical Engineering, Cell Biology, Chemical and Biomolecular Engineering, Civil Engineering, Materials Science and Engineering, Mechanical Engineering, Molecular Biology and Genetics, Pharmacology and Molecular Science, and Physics and Astronomy.

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An Integrative Graduate Education and Research Training (IGERT) grant from the National Science Foundation is funding a new graduate training program at Johns Hopkins in physical and biomolecular foundations for designing nanoprobes for the cell and other biological systems. Funded students will develop an advanced physical, materials, and biological understanding of interactions between biological probes and biological systems and become adept with the emerging concepts in genetic engineering and materials synthesis required to create probes. Hopkins departments included: Biology, Chemical and Biomolecular Engineering, Materials Science and Engineering, and Physics.

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JHU President States Leadership Goal in Nanobiotech

Johns Hopkins President William R. Brody announced at an October 28 dinner for alumni and benefactors that the Knowledge for the World campaign goal has been raised to $3.2 billion, saying that society faces formidable new challenges and more than ever needs what Hopkins produces: discoveries that make a difference. [Read more...]

Johns Hopkins Supports NIH ‘Common Fund’ for Interdisciplinary Research

Edward D. Miller, M.D., dean and chief executive officer of Johns Hopkins Medicine, spoke in support of draft legislation that encourages additional funding for the National Institutes of Health (NIH) before the U.S. House of Representatives Energy and Commerce Committee on September 19. [Read more...]

Over 100 Faculty Now Affiliated with INBT

The Institute for NanoBioTechnology now has 118 affiliated faculty members from the following Johns Hopkins institutions: School of Medicine, Krieger School of Arts and Sciences, Whiting School of Engineering, Bloomberg School of Public Health, and Applied Physics Laboratory. [Read more...]

Electric Jolt Releases Biomolecules and Nanoparticles

Johns Hopkins researchers have devised a way to use a brief burst of electricity to release biomolecules and nanoparticles from a tiny gold launch pad. The technique could someday be used to dispense small amounts of medicine on command from a chip implanted in the body… This method could be used to control the release of drug molecules; nanoparticles; biopolymers such as peptides, proteins and DNA; and protein assemblies such as viruses, said Peter C. Searson , professor of materials science and engineering and director of the Institute for NanoBioTechnology at Johns Hopkins… >> read more on JHU news

Nano Self-Folding Delivery Boxes

8/25/06 – Science News of the Week: Researchers at Johns Hopkins University have reported creating tiny two-dimensional cutouts that fold themselves up into porous cubes and other 3D containers… Team leader David Gracias, a chemical engineer, says the idea for porous nanocontainers grew out of decades of work in patterning computer chips… read more in Science >>

read theĀ research paperĀ in Journal of the American Chemical Society

Protein Switches for Cancer Therapy

Through the INBT website, Johns Hopkins University cancer researchers Anirban Maitra and James R. Eshleman in the Department of Pathology found Marc Ostermeier in Chemical and Biomolecular Engineering. Ostermeier’s group creates molecular switches by joining two unrelated proteins in which one biochemical partner controls the activity of the other. The team is now synthesizing new protein switches that recognize cancer cells. When these molecular switches identify the cancer cells, a therapeutic function is then activated. While this new approach is far from clinical trials, it represents a promising new approach for targeting cancer cells. The team recently submitted a proposal entitled Selective Prodrug Activation in Cancer Cells using Molecular Switches to the American Cancer Society.

Protein switches can be created by combining a ligand-binding protein (green) and an enzyme (red) to create a protein switch whose catalytic activity is activated only in the presence of the ligand (square).

Aiming small, thinking big

NanBioTechnology Institute will involve 75-plus faculty membersJohns Hopkins is preparing to aim enormous research and educational resources at some exceedingly small targets. Drawing on the expertise of more than 75 faculty members from such diverse disciplines as engineering, biology, medicine and public health, the university will officially launch its new Institute for NanoBioTechnology on Monday, May 15, with a celebration featuring prominent speakers.

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Nanobiotechnology training will help create hybrid researchers

A $1 million grant from the Howard Hughes Medical Institute, announced today, will help create a new graduate training program in Nanotechnology for Biology and Medicine at The Johns Hopkins University. The NBMed program will provide interdisciplinary training in nanotechnology and biology to a new generation of graduate students from three schools within Johns Hopkins. The goal is to provide a broader range of knowledge and skills to people embarking on careers in biology and medicine.

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